In this VTC Research Institute Distinguished Scholar Series event, Wah Chiu, Distinguished Service Professor and the Alvin Romansky Professor of Biochemistry at the Baylor College of Medicine, will discuss how a virus is a nanoparticle that infects a host cell and replicates itself inside the cell through an elaborate pathway. Using an electron microscope and image processing, we can visualize the 3-D structures of virus particles in a cellular environment. Multiple 3-D structure snapshots of a virus infecting a bacterium uncover a detailed mechanism of viral coat protein rearrangements to accommodate DNA packaging and release during its assembly and infection processes. A structural comparison of many bacterial and animal viruses provides an architectural basis to design a synthetic nanoparticle containing DNA for biotechnology applications.
A public reception will precede this event in the VTC Cafe at 5:00 p.m.
Virginia Tech Carilion School of Medicine and Research Institute 2 Riverside Circle, Roanoke, Virginia 24016 View Map
Talks & Readings